RAD Software

1. Spada Mac Os X
2. Spada Mac Os Update
3. Spada Mac Os Catalina
4. Spada Mac Os Download

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Released:

Find splicing-led, functional changes of the proteome.

Project description

spada

spada (Splicing-led Protein Alterations Discovered Agilely) is a tool to study the functional impact of alternative splicing changes in case-control studies. The alterations are represented as isoform switches i.e. the situation when cases are best represented by one isoform, while controls are best represented by a different one. Then, spada is able to predict which protein features are changing between both isoforms, and their impact on the protein-protein interaction network.

To start using spada, simply install it with

This package has two main functionalities:

• Calculating isoform switches from case-control transcript expression data:
• Predicting the effects of splicing on the protein structure and the interactome of a set of switches:

For detailed information on how to use spada, please visit the wiki.

Documentation

Citation

If you use spada in a scientific publication, we would appreciate citations:

Climente-González, H., Porta-Pardo, E., Godzik, A., and Eyras, E. (2017). The Functional Impact of Alternative Splicing in Cancer.Cell Reports 20, 2215–2226.

Related projects

• smartas: we applied spada to transcriptomics data from the TCGA. This repository contains the code for the analyses and the main conclusions.

Release historyRelease notifications RSS feed

1.26.5

1.26.4

1.26.3

1.26.2

1.26.1

1.26

1.25.4

1.25.2

1.25.1

Spada Mac Os X

1.25.0

1.24.4

1.24.3

1.24.2

1.24.1

1.23.7

1.23.5

1.23.4

1.23.3

1.23.2

1.23.1

1.22.2

1.22.0

1.21.19

1.21.18

1.21.17

1.21.16

1.21.15

1.21.14

1.21.13

1.21.12

1.21.11

1.21.10

1.21.9

1.21.8

Spada Mac Os Update

1.21.7

1.21.6

1.21.5

1.21.3

1.21.2

1.21.1

1.20

1.19

1.18

1.17

1.16

1.15

1.14

1.13

1.12

1.11

1.10

1.9.1b3 pre-release

1.9.1b2 pre-release

1.9

1.0

Spada Mac Os Catalina

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Spada Mac Os Download